European study finds paracetamol safe in pregnancy, no autism link

LONDON, Jan 15 — A major European review has found no link between paracetamol use during pregnancy and autism or ADHD, offering reassurance to expectant mothers.

The research, led by Professor Asma Khalil of St George’s, University of London, compiled high-quality evidence from 43 studies.

"Paracetamol is safe to use in pregnancy," Khalil said.

"When used as recommended, the best available evidence does not support a causal link with autism, ADHD or intellectual disability."

The review focused on three large sibling comparison studies covering over 260,000 children assessed for autism.

These studies account for shared genetic and environmental factors within families.

Khalil initiated the review after patients questioned her following former US President Donald Trump's September comments advising against the drug.

Medical groups globally had decried Trump's remarks as lacking an evidence base.

Paracetamol is the only pain reliever considered safe for pregnant women, with doctors advising minimal use for the shortest time.

Untreated pain and fever pose risks to both the mother and the developing baby.

Professor Grainne McAlonan of King’s College London, who was not involved, praised the study for its rigorous methodology.

"I hope the findings of this study bring the matter to a close," McAlonan said.